Does Glutathione Lighten Skin?

Jun 30, 2024

Skin brightening is a part of Asian beauty standards. That’s why anything that provides a whitening effect to your skin gains traction in a short time. It’s a major reason behind the popularity of Glutathione. However, does glutathione lighten skin, or is it just a myth?

Does Glutathione Affect Skin Color?

According to the research, the effects of intravenous (IV) glutathione on skin color are uncertain and vary:

One study discovered that taking glutathione orally (500 mg/day) and using a 2% oxidized glutathione cream could lighten skin in areas exposed to sunlight. However, there wasn’t a noticeable change in areas protected from the sun.

In a clinical trial, oral glutathione (500 mg twice daily for 18 weeks) significantly reduced skin pigmentation in both diabetic patients and healthy individuals. About 85-87% of participants experienced lighter skin.

Does Glutathione Lighten Skin Permanently?

Glutathione can lighten your skin temporarily when you take it as pills or injections. However, the effects don’t last forever. Once you stop using it, your skin will gradually go back to its original color, though it might stay slightly lighter than before. 

To keep your skin lighter, you will need to keep taking glutathione and stay out of the sun. Sun exposure can make your skin darker again. Sun rays increase melanin production, which glutathione reduces. 

How Much Glutathione Should I Take for Skin Whitening?

Taking oral glutathione at 500 mg twice daily for 18 weeks can lighten skin. Over time, about 85-87% of participants noticed a change. According to melanin index measurement, both oral glutathione and cream with oxidized glutathione can lighten skin in sun-exposed areas. 

However, there was no significant change in areas unexposed to the sun. We still need more high-quality research to understand the long-term safety of oral glutathione for skin lightening.

How Does Glutathione Whitens Skin?

There’s been a lot of talk about whether glutathione can lighten skin. According to a study, a short 4-week treatment with glutathione showed positive results for a small group of people. Glutathione works in two main ways to lighten skin. 

First, it binds to tyrosinase, an enzyme that creates melanin. It is a pigment that gives skin its color, and stops it from working.

Secondly, glutathione helps whiten skin when it stops tyrosinase from becoming active. It reduces harmful molecules called free radicals in the body. They are what trigger the production of tyrosinase, which then increases melanin production in the skin.

What to Expect from Glutathione Skin Treatment?

Using glutathione for skin whitening certainly works, but it’s important to be patient. Whether you’re taking it as an injection or using a cream, it takes time to see results. It interacts with hormones inside your body. It might take a few months before you notice healthier and lighter skin.

Glutathione also helps rid your body of harmful toxins. Before starting glutathione pills or cream, it’s a good idea to talk to a skin specialist or doctor. If you’re already using other skin treatments, you might need to pause them for a while. If you have any questions or concerns, it’s always best to seek advice from an expert.

Wrapping Up

UV rays greatly affect your skin’s health. Therefore, people are always looking for ways to protect it from sun damage. Glutathione repairs sun damage, helping your skin regain its color before the sun damage. That’s why people ask, “Does glutathione whiten skin?” yes, as it reduces melanin in your skin. 

Need advice about whether you should go for Glutathione skin treatment? Visit our family medicine specialist, Dr. Harman Buttar, at Vital Clinic & Spa. Our doctor can answer all your treatment-related concerns effectively. Dial
(832) 533-8404 to reach out.